Studies on the pathogenesis of plasma cell tumors. I. Effect of cortisol on development of plasma cell tumors.

نویسندگان

  • K Takakura
  • W B Mason
  • V P Hollander
چکیده

‘I'he effect of administration of cortisol on the development of plasma (eli tumors in BAL13/c mice was studied. Mice of both sexes were injected i.p. with mineral oil. Mice injected with mm eral oil alone demonstrated peritoneal lipogranuloma, hypercel lular inflammatory 8..S(ites, sustained hyperglobulinemia and high incidence of Pla@sma cell tumor development. Cortisol treated mice failed to show these changes. Cortisol delayed dra inatically the onset of plasma cell tumor development and de creased the total incidence of this neoplasm.

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عنوان ژورنال:
  • Cancer research

دوره 26 4  شماره 

صفحات  -

تاریخ انتشار 1966